Humans have a new 'organ' interstitium: Body's 'shock absorber' discovered by researchers

The field has long known that more than half the fluid in the body resides within cells, and about a seventh inside the heart, blood vessels, lymph nodes, and lymph vessels. The organ is a body-wide network of interconnected, fluid-filled compartments supported by a meshwork of strong, flexible proteins.

Scientists said the organ called the interstitium could be the largest in the human body.

The study further said "It looks like a mesh". Located just below the skin's surface, it surrounds veins and arteries, casing the fibrous tissue present between the muscles lining our lungs, urinary system and digestive tracts.

A team of researchers from the New York University School of Medicine happened upon the discovery while studying bile ducts in cancer patients. These small areas as well as the liquid that loads them typically aren't brand-new to scientific research, yet this brand-new job suggests that we could be significantly ignoring its significance, and also the duty it plays in human makeup might be significant adequate to necessitate its labeling as a body organ. Last year, an Irish surgeon discovered the mesentery, which connects the intestine to the abdomen. Once the scientists recognized this new space through the analysis of the images of bile ducts, they rapidly recognized the interstitium throughout the body, wherever tissues moved or were compressed by force.

They believe it could help advance the understanding of cancer and many other diseases. It is suspected that this knowledge will also help with oedema - a liver disease - and even some inflammatory disorders. Scientists traditionally studied thin slices of tissue samples treated with chemicals to preserve them.

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However, the fixing process causes fluid loss and collapse of the previously fluid-filled compartments, the researchers explained.

It appears that the interstitium might have a unified function or functions.

"The direct sampling of interstitial fluid may become a powerful diagnostic tool", Theise added in an NYU news release. According to a report, they are reviewing previous studies to obtain more information on the new organ.

The recent discovery was made using a newer technology called probe-based confocal laser endomicroscopy, which provides a microscopic view of living tissues instead of fixed ones.